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SENKIRKIN

CAS No.: 2318-18-5

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Purity: 99%

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1.What is the SENKIRKIN ?

A further hepatotoxiC alkaloid present in Senecio kirkii Hook, S. renardi and Nardosrnia laevigata. The base has [α]25D - 16° (c 1.89, MeOH) or[α]15D - 6.2° (c 1.91, CHCI3). It forms colourless plates when crystallized from either Me2CO or AcOEt and yields a picrate, m.p. 225.5-226°C and a picrolonate, m.p. 109- 110°C. The ultraviolet spectrum shows a single absorption maximum at 219 mp.. Several crystalline salts and derivatives are known, e.g. the aurichloride, m.p. 182.5-183.5°C; platinichloride, m.p. 196-7°C (dec.); bitartrate, m.p. 201°C; reineckate, m.p. 169-171°C; picrate, m.p. 225- 225.5°C; picrolonate, m.p. 138°C and the methiodide, m.p. 194-6°C (dec.). The O-acetate occurs naturally (q.v.) in Senecio kirkii.

Senkirkine is a hepatotoxic pyrrolizidine alkaloid. Studies show that Senkirkine has carincogenic activity as it induced chromosomal aberrations in cultured mammalian cells as well as hepatic tumors in rats.

2.What is the CAS number for SENKIRKIN ?

The CAS number of SENKIRKIN is 2318-18-5.

More information of SENKIRKIN 2318-18-5 are:

CAS?Number

2318-18-5

Density

1.22g/cm3

Melting Point

197°C

Boiling Point

604.9°Cat760mmHg

Flash Point

319.6°C

Vapor Pressure

3.72E-17mmHg at 25°C

Refractive Index

1.5180 (estimate)

PSA

93.14000

LogP

0.94740

Pka

12.67±0.40(Predicted)

3.What is the molecular formula of SENKIRKIN ?

The chemical formula of?SENKIRKIN is C19H27 N O6 which containing 19 Carbon atoms,27 Hydrogen atoms,1 Nitrogen atoms and 6 Oxygen atoms,and the molecular weight, and the molecular weight of SENKIRKIN is 366.48

4.What is SENKIRKIN(2318-18-5)used for?

A further hepatotoxiC alkaloid present in Senecio kirkii Hook, S. renardi and Nardosrnia laevigata. The base has [α]25D - 16° (c 1.89, MeOH) or[α]15D - 6.2° (c 1.91, CHCI3). It forms colourless plates when crystallized from either Me2CO or AcOEt and yields a picrate, m.p. 225.5-226°C and a picrolonate, m.p. 109- 110°C. The ultraviolet spectrum shows a single absorption maximum at 219 mp.. Several crystalline salts and derivatives are known, e.g. the aurichloride, m.p. 182.5-183.5°C; platinichloride, m.p. 196-7°C (dec.); bitartrate, m.p. 201°C; reineckate, m.p. 169-171°C; picrate, m.p. 225- 225.5°C; picrolonate, m.p. 138°C and the methiodide, m.p. 194-6°C (dec.). The O-acetate occurs naturally (q.v.) in Senecio kirkii.

InChI:InChI=1/C19H27NO6/c1-5-13-10-12(2)19(3,24)18(23)25-11-14-6-8-20(4)9-7-15(16(14)21)26-17(13)22/h5-6,12,15,24H,7-11H2,1-4H3/b13-5u,14-6-

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