What is the Buparvaquone?

Buparvaquone is Yellow crystalline solid, while it's Molecular Formula is C 21 H 26 O 3 . Yellow crystalline solid Analog of antimalarial hydroxynaphthoquinones; tert-butyl derivative of Parvaquone. Antiprotozoal (Theileria)

What is the CAS number for Buparvaquone?

The CAS number of Buparvaquone is 88426-33-9.

What is Buparvaquone (88426-33-9) used for?

Buparvaquone is a synthetic antiprotozoal drug that is an analog of antimalarial hydroxynaphthoquinones and a tert-butyl derivative of Parvaquone. It is effective against various protozoan parasites, particularly Theileria, and has been widely used in veterinary medicine for the treatment and prevention of bovine theileriosis.InChI:InChI=1/C21H26O3/c1-21(2,3)14-10-8-13(9-11-14)12-17-18(22)15-6-4-5-7-16(15)19(23)20(17)24/h4-7,13-14,24H,8-12H2,1-3H3

What is the Buparvaquone?

Buparvaquone is Yellow crystalline solid, while it's Molecular Formula is C 21 H 26 O 3 . Yellow crystalline solid Analog of antimalarial hydroxynaphthoquinones; tert-butyl derivative of Parvaquone. Antiprotozoal (Theileria)

What is the CAS number for Buparvaquone?

The CAS number of Buparvaquone is 88426-33-9.

What is Buparvaquone (88426-33-9) used for?

Buparvaquone is a synthetic antiprotozoal drug that is an analog of antimalarial hydroxynaphthoquinones and a tert-butyl derivative of Parvaquone. It is effective against various protozoan parasites, particularly Theileria, and has been widely used in veterinary medicine for the treatment and prevention of bovine theileriosis.InChI:InChI=1/C21H26O3/c1-21(2,3)14-10-8-13(9-11-14)12-17-18(22)15-6-4-5-7-16(15)19(23)20(17)24/h4-7,13-14,24H,8-12H2,1-3H3

Manufacturer supply good quality Buparvaquone 88426-33-9 with stock

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Product

Buparvaquone

CAS No.: 88426-33-9

product details:

Purity: 99%

Manufacturer supply good quality Buparvaquone 88426-33-9 with stock

Molecular Formula: C₂₁H₂₆O₃
Molecular Weight: 326.436
Appearance/Colour: Yellow crystalline solid
Vapor Pressure: 0mmHg at 25°C
Melting Point: 178-184 °C
Refractive Index: 1.574
Boiling Point: 460.687 °C at 760 mmHg
PKA: 5.04±0.10(Predicted)
Flash Point: 246.536 °C
PSA： 54.37000
Density: 1.158 g/cm³
LogP: 5.12030

Buparvaquone(Cas 88426-33-9) Usage

InChI:InChI=1/C21H26O3/c1-21(2,3)14-10-8-13(9-11-14)12-17-18(22)15-6-4-5-7-16(15)19(23)20(17)24/h4-7,13-14,24H,8-12H2,1-3H3

88426-33-9 Relevant articles

Buparvaquone preparation method

-

Paragraph 0070-0076; 0082-0084, (2020/02/10)

The invention provides a buparvaquone pr...

Synthesis and antileishmanial activity of novel buparvaquone oxime derivatives

Maentylae, Antti,Rautio, Jarkko,Nevalainen, Tapio,Vepsaelainen, Jouko,Juvonen, Risto,Kendrick, Howard,Garnier, Tracy,Croft, Simon L.,Jaervinen, Tomi

, p. 3497 - 3502 (2007/10/03)

Novel oxime derivatives (2, 3 and 5) of ...

Antiprotozoal agents

-

, (2008/06/13)

Novel combinations of an antiprotozoal n...

In vitro activity of 2-cycloalkyl-3-hydroxy-1,4-naphthoquinones against Theileria, Eimeria and Plasmodia species

Hudson,Pether,Randall,et al.

, p. 271 - 275 (2007/10/02)

88426-33-9 Process route

: C₂₁H₂₅BrO₂

: 88426-33-9
2-[trans-(4-t-butylcyclohexyl)methyl]-3-hydroxy-1,4-naphthoquinone

Conditions

Conditions	Yield
With water; In 1,2-dichloro-ethane; at 75 - 80 ℃; for 2h;	91.3%

: 3-(trans-4-tert-butyl-cyclohexylmethyl)-2-hydroxy[1,4]naphthoquinone-1-oxime

: 86790-15-0,88426-33-9
3-hydroxy-2-(trans-4-tert-butylcyclohexyl)methylnaphtho-1,4-quinone

Conditions

Conditions	Yield
With phosphate buffer; liver microsomes from rats treated with dexamethasone; NADPH; magnesium chloride; In ethanol; water; at 37 ℃; for 24h; pH=7.4;